Abstract
In the present study, the effect of methamphetamine (MAP) on histamine (HA) release measured by in vivo brain microdialysis in the rat hypothalamus was investigated. Administration of MAP (3mg/kg) significantly increase HA release form 40 to 160 min after the injection. This finding suggest that a moderate close of MAP activates the hypothalamic HA neuron system, which may be related to effects of MAP on intrinsic biological rhythms.
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Ito, C., Onodera, K., Yamatodani, A., Watanabe, T., & Sato, M. (1997). The effect of methamphetemine on histamine release in the rat hypothalamus. Psychiatry and Clinical Neurosciences, 51(2), 79–81. https://doi.org/10.1111/j.1440-1819.1997.tb02911.x
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