Progeria (hutchinson-gilford syndrome) report of a case and review of the literature

Abstract

A classical case of progeria is described. The world literature relating to this subject is reviewed and it is concluded that this is the nineteenth typical case to be reported. Approximately as many atypical cases have been described and a separate grouping and naming of these is advocated. The clinical features, diagnosis, pathology, and treatment of progeria are discussed. It is suggested that dysfunction of the anterior lobe of the pituitary, possibly of the eosinophil cells, is the underlying lesion.