P55 The occupations associated with COPD risk in the large population-based UK Biobank cohort study

Abstract

Introduction and objectives COPD is one of the leading causes of morbidity and mortality worldwide. Exposure to occupational hazards is an important and preventable risk factor. However, the contribution of each occupation to COPD risk in a general population is uncertain. Our aim was to investigate the association of COPD with occupation in a large UK population-based study. Methods Between 2006 and 2010 the UK Biobank cohort recruited 502,649 subjects aged 40-69 years. COPD cases were defined by spirometry-based FEV1/FVC