APC Targeting: mRNA Delivery System for Targeting Antigen‐Presenting Cells In Vivo (Adv. Healthcare Mater. 17/2018)

Abstract

Abstract The study in article 1800335 by Salvador Borrós and co‐workers, takes advantage of the known versatile properties of the oligopeptide end‐modified poly ( β ‐amino esters) (OM‐PBAEs) to complex mRNA and form nanoparticles. It is demonstrated that the selection of the appropriate end‐oligopeptide modifications enables the specific targeting and major transfection of antigen‐presenting cells (APC) in vivo, after intravenous administered.