Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma

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Abstract

Proteogenomic characterization of HBV-related hepatocellular carcinoma (HCC) using paired tumor and adjacent liver tissues identifies three subgroups with distinct features in metabolic reprogramming, microenvironment dysregulation, cell proliferation, and potential therapeutics.

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Gao, Q., Zhu, H., Dong, L., Shi, W., Chen, R., Song, Z., … Fan, J. (2019). Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma. Cell, 179(2), 561-577.e22. https://doi.org/10.1016/j.cell.2019.08.052

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