A Clinical Study to evaluate the efficacy of Papaya Ksheera based Sphatika Ksharasutra in Bhagandara w.s.r. to fistula-in-ano

Abstract

Background: Bhagandara is one among Ashtamahagadas mentioned by Acharya Sushruta and is one of the most common ailments pertaining to ano rectal region. Management of Fistula -in-ano has become a challenge to Allopathy Surgeons because of its complications like post-operative pain, wound management, recurrence and incontinence. In Ayurveda, the effective treatment is Ksharasutra ligation. Snuhi Ksheera based Apamarga Ksharasutra is the standard one and is proved effective treatment in the management of Fistula-in-ano. But, burning sensation, pain, local irritation during the course of therapy and difficulty in manufacturing process has limited its use. To overcome these lacunas, present study has been carried out. Objectives: To evaluate the significance of Papaya Ksheera based Sphatika Ksharasutra by comparing with the efficacy of Snuhi Ksheera based Apamarga Ksharasutra in the management of Bhagandara. Materials and methods: A total of 40 patients were randomly allotted into two groups namely Group A with trail drug i.e. Papaya Ksheera based Sphatika Ksharasutra and Group B as Control group i.e. Snuhi Ksheera based Apamarga Ksharasutra with 20 patients in each group. Results: Assessment of Pain, Discharge, Pruritis ani, length of track was made. In Group A, overall result is 98.5% and Group B overall result is 91.5%. The test shows that the treatment is statistically not significant in Group B when compared to Group A. Conclusion: This study showed that the trial drug was as effective as the standard drug in the treatment of Bhagandara.