Immune thrombocytopenia (ITP) in a patient with relapsing-remitting multiple sclerosis (RRMS) associated with b-interferon-1α treatment

Abstract

This paper reports a case of severe immunethrombocytopenia (ITP) associated with b-interferon-1α (Cinnovex) in a patient with relapsing remitting multiples clerosis (RRMS). A 22 year old woman with a one-year history of RRMS referred to MS Clinic due to purpuricrash. The platelet count was 6,000/μL at admission.A diagnosis ITP was made. Cinnovex was stopped. She received intravenous methylprednisolone 500mg/d, for2days, and intravenous immungloboulin (IVIG), 55mg.Thrombocytopeniare solved in the following days. She was started on CinnoMer (GlatiramerAcetate, CinnaGenCo.) for MSmanagement.There was no recurrence of thrombocytopenia in the next follow-up visits.