Abstract
A novel tetracycline antibiotic, Sch 33256, was isolated from a culture broth of a new species of Actinomadura. The antibiotic was isolated by solvent extraction, Sephadex G-25 column chromatography and crystallization. The structure was determined by comparison of the spectra with that of chlortetracycline. Spectroscopic analysis of the compound yielded 2’-N-methyl-8-methoxychlortetracycline as the proposed structure. © 1987, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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Patel, M., Gullo, V. P., Hegde, V. R., Horan, A. C., Gentile, F., Marquez, J. A., … Waitz, J. A. (1987). A Novel Tetracycline From Actinomadura Brunnea Fermentation, Isolation And Structure Elucidation. The Journal of Antibiotics, 40(10), 1408–1413. https://doi.org/10.7164/antibiotics.40.1408
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