From e-health to Personalised Medicine

Abstract

The research agenda of the TBS group is aiming at offering a complete solution for the management of molecular medicine in the standard care environment. The impact of the different -omics (genomics, proteomics, metabolomics,...) is already representing a very important part of the research effort in medicine and is expected to modify dramatically the model of delivery of healthcare service. The TBS group is facing this challenge through a R&D effort in order to transform its Clinical Information System into a complete suite for the management of clinical research and care pathways, supporting a completely personalised approach. The IT suite allows research to integrate the Electronic Clinical Records with data from technologies such as DNA and protein microarrays, data from diagnostic and molecular imaging, and workflow management solution. In this paper we will discuss the results from the participation to different European and national research projects, sharing this development aim. We provided the IT integration suite for projects for the identification of therapy- relevant mutations of tumor suppressor genes in colon cancer (MATCH EU project), for the genetic base for the impact of metabolic diseases on cardiovascular risk (MULTIKNOWLEDGE EU project) and for the identification of biomarkers for Parkinson disease (SYMPAR project in Italy).