A REVIEW ON NANOTECHNOLOGY-DRIVEN GREEN SYNTHESIS OF SILVER NANOPARTICLES USING NIGELLA SATIVA

Abstract

Background: Nanotechnology has revolutionized modern science by enabling the synthesis of nanoparticles with unique physicochemical properties. Among these advancements, green synthesis using plant-based resources has gained significant attention for being eco-friendly and cost-effective. Nigella sativa (black seed), known for its rich bioactive compounds like alkaloids, flavonoids, and phenolics, has traditionally been used for treating various ailments. Body: This review focuses on the green synthesis of silver nanoparticles (AgNPs) using Nigella sativa as a nanotechnology-driven resource. The process leverages plant extracts to produce AgNPs, showcasing reduced toxicity and environmental impact compared to conventional physical and chemical methods. Key topics include the historical evolution of nanotechnology, top-down and bottom-up synthesis approaches, and the superior antimicrobial and biomedical applications of AgNPs due to their high surface area to volume ratio. The potential of N. sativa in producing nanomaterials highlights its importance in sustainable nanotechnology for diagnostics, antimicrobial therapies, and other applications. Conclusion: The incorporation of nanotechnology and green synthesis has positioned Nigella sativa as a promising resource for environmentally safe and biocompatible nanoparticle synthesis. Its role in modern science underscores its potential in addressing global challenges in medicine and environmental management.