Vigilancia de la resistencia de levaduras a antifúngicos

Abstract

Invasive fungal infections have significantly increased over the last 20 years and, despite Candida albicans continues to be the main candida species, other species are emerging. Resistance to antifungal drugs is also emerging. We studied the resistance pattern to Amphotericin B and azole agents in 110 blood or other normally sterile sites yeasts clinical isolates. Overall, 5% resistance to azoles was detected and 100% were sensitive to Amphotericin B. The aim of this work is to review the trends in yeasts resistance from Chile and other countries, and to warrant the maintenance of a resistance fungal surveillance program.