Scale-up of liquid-liquid phase mixing vessel

Abstract

The scale-up effect of mixing vessels on the drop size of a liquid-liquid dispersion is discussed and correlative equations to estimate drop sizes in breakup and coalescence regions are proposed. It is shown that (n3 d2 D)(4Np/π) is applicable as a scale-up standard and that the average energy dissipation rate, the Weber number in the mixing vessel or the agitational Reynolds number is not a satisfying scale-up standard. It is also shown that the effect of volume fraction of dispersed phase on drop size is affected by the scale-up ratio; that is, the scale-up ratio is expected to have a smaller effect on drop size as the fraction of dispersed phase increases. © 1987, The Society of Chemical Engineers, Japan. All rights reserved.