Correction: A systems immunology perspective on gout pathogenesis and its precision-targeted treatment strategies (Frontiers in Immunology, (2025), 16, (1615914), 10.3389/fimmu.2025.1615914)

Abstract

Inflammation Reference “30” was not cited in the article. The citation has now been inserted in the scetion 2 Immunological pathogenesis of gouty arthritis, 2.4 NOD-like receptors and inflammasome activation in GA pathogenesis, 4 and should read: “Upon binding to these receptors, MSU crystals trigger downstream signaling via the adaptor protein MyD88, leading to IL-1βrelease and neutrophil infiltration, ultimately contributing to the inflammatory cascade characteristic of gout arthritis (GA) (29, 30)” Reference “16” was erroneously written as “Posada Arias S, Rey-Suárez P, Pereáñez JA, Acosta C, Rojas M, Delazari Dos Santos L, et al. Isolation and functional characterization of an acidic myotoxic phospholipase A2 from Colombian bothrops asper venom. Toxins (Basel). (2017) 9:342. doi: 10.3390/toxins9110342”. It should be “Shirai T, Hilhorst M, Harrison DG, Goronzy JJ, Weyand CM. Macrophages in vascular inflammation–From atherosclerosis to vasculitis. Autoimmunity. (2015) 48:139-151. doi:10.3109/08916934.2015.1027815”. Reference for “22” was erroneously written as “Yagnik DR, Florey O, Philippidis P, Emons V, Mason JC, Haskard DO, et al. Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages. Arthritis Rheumatol. (2002) 46:3026–33. doi: 10.1002/art.v46:11”. It should be “Yagnik DR, Florey O, Philippidis P, Emons V, Mason JC, Haskard DO, et al. Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages. Arthritis Rheumatol. (2002) 46:3026–33. doi: 10.1002/art.10614”. Reference for “23” was erroneously written as “Renaudin F, Orliaguet L, Castelli F, Fenaille F, Prignon A, Alzaid F, et al. Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages. Ann Rheum Dis. (2020) 79:1506–14. doi: 10.1136/annrheumdis-2020-217342”. It should be “So AK, Martinon F. Inflammation in gout: mechanisms and therapeutic targets. Nat Rev Rheumatol. (2017) 13:639-647. doi:10.1038/nrrheum.2017.155”. Reference “25” was erroneously written as “Russell IJ, Papaioannou C, McDuffie FC, MacIntyre S, and Kushner I Effect of IgG and C-reactive protein on complement depletion by monosodium urate crystals. J Rheumatol. (1983) 10:425–33”. It should be “Shi M, Luo J, Ding L, Duan L. Spontaneous resolution of acute gout: mechanisms and therapeutic targets. RMD Open. (2023) 9:e003586. doi:10.1136/rmdopen-2023-003586”. Reference “26” was erroneously written as “Jung J, Bong JH, Lee SJ, Kim MJ, Sung JS, Lee M, et al. Screening of fv antibodies with specific binding activities to monosodium urate and calcium pyrophosphate dihydrate crystals for the diagnosis of gout and pseudogout. ACS Appl Bio Mater. (2021) 4:3388–97. doi: 10.1021/acsabm.0c01680”. It should be “Busso N, So A. Mechanisms of inflammation in gout. Arthritis Res Ther. (2010) 12:206. doi:10.1186/ar2952”. Reference “27” was erroneously written as “Type II collagen facilitates gouty arthritis by regulating MSU crystallisation and inflammatory cell recruitment. Ann Rheum Dis. (2023) 82:416–27. doi: 10.1136/ard-2022-222764”. It should be “Scanu A, Oliviero F, Ramonda R, Frallonardo P, Dayer JM, Punzi L. Cytokine levels in human synovial fluid during the different stages of acute gout: role of transforming growth factor β1 in the resolution phase. Ann Rheum Dis. (2012) 71:621-624. doi:10.1136/annrheumdis-2011-200711”. Reference “32” was erroneously written as “Sharma K, Dresser K, and Shi Y. A role of lgM antibodies in monosodium urate crystal formation and associated adjuvanticity. Immunol. (2009) 182:1912–8. doi: 10.4049/iimmunol.0803777”. It should be “Martinon F, Pétrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. (2006) 440:237-241. doi:10.1038/nature04516”. Reference “33” was erroneously written as “Elmaoued RA, Davis AS, Kyei G, and Deretic V. Toll-like receptors control autophagy. EMBO J. (2008) 27:1110–21. doi: 10.1038/emboi.2008.31”. It should be “Zamudio-Cuevas Y, Fernández-Torres J, Martínez-Nava GA, et al. Phagocytosis of monosodium urate crystals by human synoviocytes induces inflammation. Exp Biol Med (Maywood). (2019) 244:344-351. doi:10.1177/1535370219830665”.