Efficient metal salt catalyzed azidolysis of epoxides with sodium azide in acetonitrile

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Abstract

A new, simple, efficent, completely anti stereoselective method for the azidolysis of 1,2 epoxides with NaN3 in acetonitrile, by means of metal salts, is described. The use of a non-protiu solvent makes this method very competitive with the other methods previously reported. © 1990.

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Chini, M., Crotti, P., & Macchia, F. (1990). Efficient metal salt catalyzed azidolysis of epoxides with sodium azide in acetonitrile. Tetrahedron Letters, 31(39), 5641–5644. https://doi.org/10.1016/S0040-4039(00)97921-8

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