Clinical observation of minocycline hydrochloride ointment in the treatment of initial peri-implant inflammation

Abstract

To observe and analyze the therapeutic efficacy of minocycline hydrochloride ointment in the treatment of initial peri-implant inflammation, a total of 180 patients with initial peri-implant inflammation and treated at the Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital were enrolled. The patients were divided into the control group and the research group, with 90 patients in each group. Of those, patients in the research group were applied with minocycline hydrochloride ointment, while 10 % of iodine was placed around the teeth in patients of the control group. The therapeutic outcome was observed and compared between these groups. Comparison of the plaque index of both groups after treatment indicated that the outcome of the research group was better than that of the control group (P<0.05). The probing depth and sulcus bleeding index of the research group was significantly superior than that of the control group (P<0.05). Application of minocycline hydrochloride ointment in the treatment of initial peri-implant inflammation could significantly improve the therapeutic outcome.