Aldose reductase inhibitors from Stellera chamaejasme

Abstract

Six biflavonoids (chamaejasmin, 7-methoxyneochamaejasmin, 7-methoxychamaejasmin, chamaejasmenin B, chamaechromone, wikstrol A) from Stellera chamaejasme L. have been assayed to show good aldose reductase inhibiting activity. These compounds may be useful to improve diabetic complications such as neuropathy, cataract formation, neophropathy, and retinopathy. © 2005 Taylor & Francis Ltd.