Abstract
Two new stilbene derivatives, named strebluses C and D, were isolated from the EtOAc-soluble fraction of the stems of Streblus ilicifolius (Moraceae). Its absolute configuration was elucidated based on NMR spectroscopic data interpretation and optical rotation calculation. Streblus C possesses strong tyrosinase inhibitory activity with an IC50 value of 0.01 μM. Docking studies of 1 and 2 with oxy-tyrosinase were carried out to analyze their interactions. The analysis of the docked poses confirmed that 1 showed better binding affinity for oxy-tyrosinase than that of 2.
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CITATION STYLE
Nguyen, N. T., Dang, P. H., Nguyen, H. X., Do, T. N. V., Le, T. H., Le, T. Q. H., & Nguyen, M. T. T. (2021). Tyrosinase Inhibitors from the Stems of Streblus Ilicifolius. Evidence-Based Complementary and Alternative Medicine, 2021. https://doi.org/10.1155/2021/5561176
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