A routine urine test has partial predictive value in premature rupture of the membranes

Abstract

Objective: This study aimed to examine the predictive value of a routine urine test for premature rupture of the fetal membranes. Methods: Routine urine test data of 100 patients with preterm premature rupture of the membranes (PPROM) and 100 patients with full-term premature rupture of the membranes (PROM) were collected by the case-based method. Additionally, 100 healthy pregnant women and 100 nonpregnant adult healthy women were selected as the negative control group and blank control group, respectively. A receiver operating characteristic curve was established after identifying the different parameters. Results: We found that occult blood, glucose, ketone bodies, urine specific gravity, red blood cell count, epithelial cell count, bacteria, yeast, crystals, and electrical conductivity were significantly different between the PPROM and PROM groups. There were significant differences in occult blood, protein, glucose, ketone bodies, pH, red blood cell count, bacteria, urine specific gravity, crystals, and electrical conductivity between the PPROM and full-term groups. Receiver operating characteristic curve analysis showed that when the cut-off for bacteria was 130.15, it had the largest area under the curve value of 0.696. Conclusion: A routine urine test, especially for bacterial counts, has certain predictive value for PROM.