Brine shrimp lethality assay of Bacopa monnieri

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Abstract

Successive petroleum ether, chloroform, ethanol and water extracts, a saponin rich fraction (SRF) and bacoside A isolated from Bacopa monnieri were tested for brine shrimp lethality. Successive ethanol extracts and SRF showed potent activity. Bacoside A showed the maximum activity with a LC50 of 38.3 μg/mL. The results confirmed the previous reports of an anticancer effect of Bacopa monnieri and suggest bacoside A as the active constituent. © 2002 John Wiley & Sons, Ltd.

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D’Souza, P., Deepak, M., Rani, P., Kadamboor, S., Mathew, A., Chandrashekar, A. P., & Agarwal, A. (2002). Brine shrimp lethality assay of Bacopa monnieri. Phytotherapy Research, 16(2), 197–198. https://doi.org/10.1002/ptr.1001

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