Abietane diterpenes from Hyptis platanifolia

Abstract

Three new abietane diterpenes 19-oxo-inuroyleanol, 11,14-dihydroxy-12- methoxy-7-oxo-8,11,13-abietatrien-19,20β-olide and 19,20-epoxy-12-methoxy- 11,14,19-trihydroxy-7-oxo-8,11,13-abietatriene, in addition to inuroyleanol, and coulterone were isolated from roots of Hyptis platanifolia. Investigation of the aerial parts yielded a mixture of the steroids stigmasterol and β-sitosterol, and the triterpenes betulinic and ursolic acids. Structural characterization of all compounds was established on the basis of spectroscopic methods, particularly 1D and 2D NMR, and comparison with data from literature. ©2005 Sociedade Brasileira de Química.