Lung Cancer Prevention and Therapy Using the JinFuKang Herbal Mixture

Abstract

Traditional Chinese Medicine (TCM) plays an indispensable role in China for both cancer prevention and adjuvant treatment in platinum-based chemotherapy. A number of naturally occurring products from Chinese herbal extracts have shown inhibitory effects against carcinogenesis. One example is JinFuKang which is a mixture of 12 Chinese herbs and has been used widely in China for the prevention and treatment of lung cancer. JinFuKang has been shown to inhibit tumor growth in human lung and liver cancer xenograft mouse models. Among all the herbal agents that contain the Astragalus membranaceus (Fisch), JinFuKang was found to be effective in improving the 24-month survival of lung cancer patients in combination with platinum-based chemotherapy. This review article will discuss the application of JinFuKang to cancer prevention and treatment.