Antimicrobial activity of serial extracts from of Aeglemarmelos(linn.) Against dysenteric causing gram negative organisms

Abstract

Abstract:The in vitro antimicrobial activity of methanol extracts from Leaves , stream , bark , fruit of Aeglemarmeloswere investigated against bacterial and fungal species. All the extracts exhibitedbroad spectrum antimicrobial activity with zones of inhibition ranging from 10 to 22 mm against bacteriashigelladysenteriae, shigellaflexneri, vibrio cholerae, vibrio parahaemolyticus, Escherichia coli, salmonella typhi, The minimal inhibitory concentrations (MIC) and the minimal microbicidal concentrations(MMC) of the extracts ranged from 1.25 to 10 mg/mL and 2.5 to 20 mg/mL respectively. Assessment of antibacterial efficacy of different extract revealed that The ability of the leaf extracts of Aeglemarmelosto inhibit growth of bacteria and fungi isan indication of its broad spectrum antimicrobial activity which could be a potential source for development ofnovel bioactive antimicrobial agents.