A Comparison of vitamin D deficiency with neutrophil lymphocyte ratio and CRP levels in Covid-19 patients

Abstract

Objective: Objective: We aimed to evaluate the association of neutrophil-lymphocyte ratio (NLR) and C reactive protein (CRP), ferritin, sedimentation levels with vitamin D concentrations in Covid-19 patients and to investigate  their effect of  levels on Covid-19 patients. Materials and Methods: Forty-six patients aged 18-85 were included in our study. Our study is a retrospective study. Patients were divided into 2 groups with the first group consisting of those with vitamin D level 20 and below and 2nd group consisting of those with vitamin D level above 20. After Vitamin D, CRP, neutrophil, and lymphocyte values were retrospectively investigated with the hospital database, vitamin D levels were compared to CRP and neutrophil/lymphocyte ratio.  Results: A positive correlation between CRP and SED, CRP and ferritin, NLR, and ferritin was observed in Covid-19 positive patients with Vitamin D level > 20. A positive correlation between NLR and CRP was observed in Covid-19 positive patients with Vitamin D level ≤ 20. Conclusion: In patients with Vitamin D levels >20, there was a significant correlation between vitamin D and NLR and a moderate correlation between Vitamin D and CRP. In patients with Vitamin D levels <20, there was a positive correlation of Vitamin D with CRP and NLR.