Platelet metabolism meets thrombosis

Abstract

Metabolic pathways intersect with many processes important in hematology, including thrombosis, innate and adaptive immunity, malignant transformation, and stem cell function. These pathways are increasingly recognized as potentially targetable for therapeutic intervention. In this issue of Blood, Lepropre et al identify the energy sensor AMP-activated protein kinase (AMPK) in platelets as a regulator of thrombosis.1.