Virus Evasion of MHC Class I Molecule Presentation

  • Petersen J
  • Morris C
  • Solheim J
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Abstract

The MHC class I H chain and the L chain that assembles with it, β2-microglobulin (β2m),[3][1] are cotranslationally inserted into the lumen of the endoplasmic reticulum (ER) ([1][2]). In the ER, the MHC/β2m heterodimer binds peptide that is generated by proteasomal protein degradation in the

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Petersen, J. L., Morris, C. R., & Solheim, J. C. (2003). Virus Evasion of MHC Class I Molecule Presentation. The Journal of Immunology, 171(9), 4473–4478. https://doi.org/10.4049/jimmunol.171.9.4473

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