Laser induced clot formation in blood treated by EDTA

Abstract

Patients under systemic (ethylenediaminetetra-acetic acid) EDTA are at risk of hemorrhage for any accidental trauma even the superficial ones. This research is a trial to use 980 nm wavelength laser light to provide coagulation for such pa-tients in a local region without collateral thermal damage. Material and Method: 980 nm Diode laser operating in a continuous mode (CW) was incident on human blood treated with EDTA in Durham tubes. The used parameters were (2.25, 3, 3.75 and 6.75) W output power for variable exposure times (1, 3, 9 and 27) s. Results: A homogenous clot was performed at 4327.84 J/cm 2 deposited energy density with the ab-sence of any thermal stress in the blood. Con-clusion: 980 nm laser wavelength provides a local photochemical bond break of the antico-agulant enhancing blood coagulation for medi-cally compromised patients.