Abstract
A new ionone glycoside, frehmaglutoside I (1), and three new rhemaneolignans A-C (2-4) were isolated from the 95% EtOH extract of the roots of Rehmannia glutinosa. Their structures were determined by extensive spectroscopic (UV, IR, HR-ESI-MS, 1D and 2D NMR) analyses. In addition, these compounds were evaluated for their protective effects on cardiocytes impaired by doxorubicin in H9c2 cells. Among them, compounds 1-3 exhibited protective effects against DOX-induced cardiotoxicity.
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Li, M., Wang, X., Zheng, X., Wang, J., Zhao, W., Song, K., … Feng, W. (2015). A new ionone glycoside and three new rhemaneolignans from the roots of rehmannia glutinosa. Molecules, 20(8), 15192–15201. https://doi.org/10.3390/molecules200815192
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