What value for the phase IV clinical trials?

Abstract

Phase IV of clinical trials also named post marketing studies or real world trials, are useful to better understand the true efficacy of medicines. Phase IV could improve scientific knowledge i.e. side effects, use of a drug in special conditions, better precision of the dosage. But some studies are more designed for economic purposes facilitating product promotion. So there are several kinds of phase IV clinical trials: clinical research, seeding trials, prescription studies or pseudo-trials for commercial purposes. Keywords: Phase IV clinical trials; Post marketing studies; Real world trials