The significance of elevated CSF lactate

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Abstract

The final diagnosis of 158 patients who had a cerebrospinal fluid (CSF) lactate concentration greater than 2 mmol/l was ascertained. The conditions included seizures, inflammatory changes, and proven metabolic disorders. For the diagnosis of congenital lactic acidoses, CSF lactate should ideally be measured in a seizure free patient after any acute illness.

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Chow, S. L., Rooney, Z. J., Cleary, M. A., Clayton, P. T., & Leonard, J. V. (2005). The significance of elevated CSF lactate. Archives of Disease in Childhood, 90(11), 1188–1189. https://doi.org/10.1136/adc.2005.075317

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