Síndrome febril sin foco y sospecha de infección bacteriana en niños entre 6 semanas y 36 meses

Abstract

Background: Unknown fever (UF) is a frequent pathology in children and its main etiology are viral infections. The identification of bacterial infection with antibiotics requirements is still on debate. Objective: Determine the characteristics of patients with suspicion of an invasive bacterial infection (IBI) and evaluate the contribution of C reactive protein (CRP) and leukocytes with absolute neutrophyl count (ANC). Method: Prospective-descriptive study of 640 patients between 6 weeks and 36 months-old, with UF and IBI suspicion, admitted in Infectology from the Emergency Room of Hospital Sótero del Río between 2005 - 2007. Results: 53,7% of cases had a confirmed IBI, most commonly urinary tract infection (80,17%). A significantly difference was found between CRP, leukocytes and ANC, but the Roc curve did not show a relevant difference. It was not possible to determine a specific level of CRP, leukocytes and ANC for a better IBI discrimination.