A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade

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Abstract

A diastereoselective approach to axially chiral imidazopyridine-containing biaryls has been developed. The reactions proceed through a radical cyclization cascade to construct the biaryls with good to excellent central-to-axial chirality transfer.

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Yan, H., Mao, Z. Y., Hou, Z. W., Song, J., & Xu, H. C. (2019). A diastereoselective approach to axially chiral biaryls via electrochemically enabled cyclization cascade. Beilstein Journal of Organic Chemistry, 15, 795–800. https://doi.org/10.3762/bjoc.15.76

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