Validity of PROMIS physical function in patients with hip dysplasia treated with periacetabular osteotomy

Abstract

Hip dysplasia is known to lead to pain, disability, depression and eventually secondary hip osteoarthritis in young adults. Performance of the Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) Computer Adaptive Test (CAT) in hip dysplasia patients indicated for periacetabular osteotomy (PAO) is unknown. The aim of this investigation was to validate the use of PROMIS PF CAT with currently accepted patient-reported outcome (PRO) instruments in young adults with hip dysplasia indicated for PAO. Individuals indicated for PAO to treat symptomatic hip dysplasia were identified and consented to complete the PROMIS PF CAT, Hip disability and Osteoarthritis Outcome Score Physical Function Shortform (HOOS-PS), modified Harris hip score (mHHS) and International Hip Outcome Tool-12 (iHOT-12) questionnaires during their pre-operative visit to test correlations between instruments as part of the validation of PROMIS PF CAT. The relationship between PRO instruments was compared using Spearman correlation coefficients. Correlation between PRO instruments were defined as high (>0.7), high-moderate (0.61–0.69), moderate (0.4–0.6), moderate-weak (0.31–0.39) and weak (≤0.3). Forty-one individuals to undergo PAO were enrolled. The PROMIS PF CAT correlated moderate to high and demonstrated construct validity with traditionally used hip PRO instruments. Additionally, the question burden was decreased with no floor or ceiling effects observed. In conclusion, PROMIS PF CAT is an efficient and valid tool for pre-operative clinical assessment of pain and disability hip dysplasia patients undergoing PAO.