Prenatal diagnosis of VACTERL association after early‐first trimester SARS‐COV‐2 infection

Abstract

Organogenesis is a period of fetal development with a special vulnerability to biological and environmental agents. There are some viral infections whose transmission in the first trimester carries a significant risk for the development of congenital anomalies. Although the possibility of vertical transmission of SARS‐CoV‐2 during pregnancy has been demonstrated, there are no studies evaluating the impact of SARS‐CoV‐2 infection in the first trimester and its possible association with congenital anomalies. In this communication, we present the case of a pregnant woman with early SARS‐CoV‐2 infection, prenatally diagnosed with fetal VACTERL association by mid‐trimester ultrasound. Further studies are needed to determine the causal association.