Placenta related pathogenic factors for preeclampsia

Abstract

Preeclampsia (PE) is a life-threatening complication of pregnancy. The precise origin of PE remains obscure. Placenta has been considered to play a central role in its pathology. Here we present a brief overlook of placenta related pathogenic factors that might be involved in the pathology changes of PE. A series of factors that correlated with placenta pathology have been regarded attributed to the mechanism of the disease. Some of the factors may be confirmed to be useful biomarkers in the early prediction and monitoring of the disease in a future.