Antibody Immobilization in ZnO-Thin Film Transistors for Low-Cost Biosensors Applications †

Abstract

The antibody immobilization with low-cost materials and label-free methods are a challenge for the fabrication of biosensor devices. In this work, it was developed a strategy for antibody immobilization on ZnO TFTs over polyethylene terephthalate (PET) as a recyclable plastic substrate. Antibodies were biofunctionalized using a label-free strategy for E. coli detection. The use of a recyclable plastic substrate PET enables the compatibility with flexible electronics that could contribute for a low-cost biosensor useful in rural communities that do not have the necessary infrastructure and trained personnel for pathogenic bacterial detection in food or water.