2-Pyrone natural products and mimetics: Isolation, characterisation and biological activity

Abstract

The review summarises natural products containing the 2-pyrone moiety. An emphasis has been placed upon the biological activity associated with 2-pyrones, particularly with respect to potential therapeutic or anti-microbial agents. Where appropriate, non-natural 2-pyrone analogues are discussed, particularly those derived from natural product lead compounds. © The Royal Society of Chemistry 2005.