Fahr’s disease: A rare neuro-degenerative disorder

Abstract

Fahr’s disease is a rare, autosomal dominant/sporadic inherited neurological disorder characterised by abnormal deposits of calcium in areas of Basal Ganglia, Thalamus, Hippocampus, Cerebral cortex, Cerebellum, and Dentate Nucleus. Clinical manifestations of this disease incorporate a wide variety of symptoms, ranging from neurological symptoms involving extrapyramidal system to neuropsychiatric abnormalities of memory and concentration to movement disorders including Parkinsonism, chorea, and tremors. These symptoms generally occur later in the course of the disease. Age of onset is typically in the 40s or 50s, although it can occur at any time during life. We are presenting a case of Fahr's disease in a 56-year-old female who presented with chronic headache, focal seizures, Parkinsonism and psychiatric symptoms.