Whole Genome Duplication in the Genomics Era: The Hidden Gems in Invertebrates?

Abstract

Whole genome duplication (WGD) events generate potent new genomic resources for rewiring existing genetic regulatory networks. Studying WGDs in vertebrates is of considerable importance to understand vertebrate evolution. Recent studies have shown that different invertebrate lineages, including lophotrochozoans/spiralians and ecdysozoans, have also undergone WGDs. Here we summarize recent developments and argue that more studies of WGD events in different invertebrate lineages are required to better understand the molecular evolution of metazoans.