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Wnt/β-catenin signaling and disease

Cell
DOI: 10.1016/j.cell.2012.05.012
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Abstract

The WNT signal transduction cascade controls myriad biological phenomena throughout development and adult life of all animals. In parallel, aberrant Wnt signaling underlies a wide range of pathologies in humans. In this Review, we provide an update of the core Wnt/β-catenin signaling pathway, discuss how its various components contribute to disease, and pose outstanding questions to be addressed in the future. © 2012 Elsevier Inc. © 2012 Elsevier Inc.

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APA

Clevers, H., & Nusse, R. (2012, June 8). Wnt/β-catenin signaling and disease. Cell. Elsevier B.V. https://doi.org/10.1016/j.cell.2012.05.012

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