Impact of “high” implantation on functionality of self-expandable bioprosthesis during the short- and long-term outcome of patients who undergo transcatheter aortic valve implantation: Is high implantation beneficial?

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Abstract

Aim: High position of the self-expandable bioprosthesis CoreValve/Evolut R has been proved to affect immediate hemodynamics of the valve. Whether this may have any impact on long-term procedural outcome has not been defined yet. The purpose of this study was to assess whether the final position of aortic bioprosthesis affects its long-term functionality. Method: Consecutive patients (pts) who underwent successful TAVI procedure were evaluated and separated into 2 groups according to the implantation depth (ID): Group I: pts with 4 mm <4 mm). Grouping for ID did not affect all-cause 1-year mortality. Paravalvular aortic regurgitation, as well as LVEF at discharge, proved to be independent predictors of all-cause 1-year mortality when adjusted for cofactors. Conclusion: Implantation depth under 4 mm seems to have a favorable effect on long-term hemodynamic valve functionality.

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Vavuranakis, M., Kariori, M., Scott, L., Kalogeras, K., Siasos, G., Vrachatis, D., … Tousoulis, D. (2018). Impact of “high” implantation on functionality of self-expandable bioprosthesis during the short- and long-term outcome of patients who undergo transcatheter aortic valve implantation: Is high implantation beneficial? Cardiovascular Therapeutics, 36(3). https://doi.org/10.1111/1755-5922.12330

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