Journal Article

DNA detection on lateral flow test strips: Enhanced signal sensitivity using LNA-conjugated gold nanoparticles

Chemical Communications (2012) 48(62) 7714-7716
DOI: 10.1039/c2cc33430e
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Abstract

A lateral flow test strip assay, enabling sensitive detection of DNA specific to the foodborne pathogen E. coli O157:H7, is described. The use of LNA-conjugated gold nanoparticle probes, along with signal amplification protocols, results in minimum detectable concentrations of ∼0.4 nM. © 2012 Royal Society of Chemistry.

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Rastogi, S. K., Gibson, C. L. M., Branen, J. R., Aston, D. E., Branen, A. L., & Hrdlicka, P. J. (2012). DNA detection on lateral flow test strips: Enhanced signal sensitivity using LNA-conjugated gold nanoparticles. Chemical Communications, 48(62), 7714–7716. https://doi.org/10.1039/c2cc33430e

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