Strobilurin N and two metabolites related to chorismic acid from the fruit bodies of Mycena crocata (Agaricales)

Abstract

Strobilurin N (1), a new member of the strobilurin family of antibiotics, has been isolated from the toadstool Mycena crocata, together with dehydrochorismic acid lactone (5) and 3-[1-carboxyvinyl)oxy]benzoic acid (6), which are closely related to chorismic acid (10). Their structures were determined mainly by 1H and 13C NMR spectroscopy. Interestingly, strobilurin N is the first strobilurin without antifungal activity.