Ensemble of Handcrafted and Deep Learning Model for Histopathological Image Classification

Abstract

Histopathology is the investigation of tissues to identify the symptom of abnormality. The histopathological procedure comprises gathering samples of cells/tissues, setting them on the microscopic slides, and staining them. The investigation of the histopathological image is a problematic and laborious process that necessitates the expert’s knowledge. At the same time, deep learning (DL) techniques are able to derive features, extract data, and learn advanced abstract data representation. With this view, this paper presents an ensemble of handcrafted with deep learning enabled histopathological image classification (EHCDL-HIC) model. The proposed EHCDL-HIC technique initially performs Weiner filtering based noise removal technique. Once the images get smoothened, an ensemble of deep features and local binary pattern (LBP) features are extracted. For the classification process, the bidirectional gated recurrent unit (BGRU) model can be employed. At the final stage, the bacterial foraging optimization (BFO) algorithm is utilized for optimal hyperparameter tuning process which leads to improved classification performance, shows the novelty of the work. For validating the enhanced execution of the proposed EHCDL-HIC method, a set of simulations is performed. The experimentation outcomes highlighted the betterment of the EHCDL-HIC approach over the existing techniques with maximum accuracy of 94.78%. Therefore, the EHCDL-HIC model can be applied as an effective approach for histopathological image classification.