Facile and Controllable Growth of β-FeOOH Nanostructures on Polydopamine Spheres

Abstract

Polydopamine (PDA) has a wide range of applications in biomedicine due to its high biocompatibility and surface chemistry and because of the presence of many functional groups in it, enabling further modification. As a catechol-like material, it has chelation properties for various types of metal ions, including iron. Here, we developed a procedure that uses PDA as a template to grow iron structures β-FeOOH directly on its surface. The innovative approach of this work relies on that these structures can be obtained in neutral conditions and selective iron-ion source. The influence of iron-ion source, environment, and solution concentration on the structure and amount of resulting material is presented. The growth has been characterized over time, taking into account their photothermal, magnetic, and colloidal stability properties. Moreover, we shed new light on understanding the interaction of PDA with iron ions for the growth of iron-based nanostructure on polydopamine particles. Finally, we predict that PDA@β-FeOOH nanoparticles could be a promising material in dual therapy merging photothermal therapy (PTT) treatment and magnetic resonance imaging (MRI) contrast agents.