Is Anti-platelet Treatment Necessary for Penile Mondor’s Disease?

Abstract

Objective: The aim of this study was to determine if anti-platelet treatment would have any effect on the rate and duration of resolution in penile Mondor's disease. Materials and Methods: A retrospective review of patients diagnosed with Mondor's disease between 2014 and 2018 was conducted. The patients were divided into two groups with regard to anti-platelet treatment. Age, initial symptom, medications {[}short-term fluoroquinolone antibiotics (Ab) +/- low-dose acetyl salicylic acid (ASA)], and erectile function scores were evaluated. Moreover, ultrasonographic findings (location and length of thrombus) were noted. Results: A total of 14 patients were diagnosed with penile Mondor's disease. The mean age of the patients was 36 years (range: 18-66). The initial symptom was penile induration in all patients. Thrombus was located distally in 3, mid penile in 5 and proximally in 6. The median length of thrombus was 20 mm (range: 10-50 mm). In 13 patients (92.8\%), thrombus resolved and patients became symptom-free. The median time to resolution was 3 weeks (range: 2-7). Eight patients received Ab + ASA while 5 received Ab only. There was no statistically significant difference between the groups in terms of the rate and duration of resolution (p=1.00 and 0.55, respectively). Conclusion: Our results showed that anti-platelet treatment may be unnecessary for the treatment of penile Mondor's disease.