Journal Article

Efficient cleavage of carboxylic tert-butyl and 1-adamantyl esters, and N-Boc-amines using H2SO4 in CH2Cl2

Tetrahedron Letters (2005) 46(12) 2075-2078
DOI: 10.1016/j.tetlet.2005.01.129
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Abstract

A new procedure for the deprotection of carboxylic tert-butyl and 1-adamantyl esters, and N-Boc-amines using H2SO4 in CH2Cl2 is described. The proposed method is simple, cheap, eco-friendly and represents a valid alternative to existing ones, with special significance in large scale applications. © 2005 Elsevier Ltd. All rights reserved.

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Strazzolini, P., Misuri, N., & Polese, P. (2005). Efficient cleavage of carboxylic tert-butyl and 1-adamantyl esters, and N-Boc-amines using H2SO4 in CH2Cl2. Tetrahedron Letters, 46(12), 2075–2078. https://doi.org/10.1016/j.tetlet.2005.01.129

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