Of mice, men, and HTLV-1

Abstract

In this issue of Blood, Tezuka et al report the establishment of humanized mice infected by human T-cell leukemia virus type 1 (HTLV-1) that recapitulate adult T-cell leukemia (ATL)-like leukemic symptoms and display HTLV-1 - specific adaptive immune responses. © 2014 by The American Society of Hematology.