Primary malignant melanoma of the cervix: A case report

Abstract

Primary malignant melanoma (MM) of the uterine cervix is a rare neoplasm and the overall prognosis of patients with this disease is poor. Immunohistochemical methods and exclusion of other primary melanoma sites are used to confirm the diagnosis. In the present study, the case of a 65-year-old female patient with an MM of the uterine cervix is reported. Diagnosis was confirmed by immunohistochemical methods using human melanoma black 45 antibody and S-100 protein. The tumor was identified as stage IB1 using the International Federation of Gynecology and Obstetrics classification. Chest X-ray and abdominopelvic computed tomography results were normal. The patient subsequently underwent a radical hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy. Following combined radical surgery and chemotherapy, complete remission of the tumor was achieved. The patient has since been well for 30 months without recurrence subsequent to the surgery.