Identification of a new HLA-DRB1 allele, HLA-DRB1*1212, and confirmation of HLA-B*1586

Abstract

A novel allele, HLA-DRB1*1212, was identified by sequence-based typing. DRB1*1212 was identical to DRB*120101 at exon 2 except for a single nucleotide at position 199 from A to C, leading to amino acidic substitution from He to Leu at codon 67. We also confirmed the HLA-B*1586 in another Chinese person. Copyright © Blackwell Munksgaard 2005.