Biosynthesis of Benastatin A

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Abstract

The biosynthesis of benastatin A, produced by Streptomyces sp. MI384-DF12, has been studied by feeding experiments with 14C-and 13C-labeled compounds followed by measurement of radioactivity and 13C NMR analysis. The results indicate that benastatin A is derived from two methionine units and fourteen acetate units, condensed in the "head-to-tail" fashion of typical polyketide biosynthesis. © 1992, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

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Aoyama, T., Naganawa, H., Muraoka, Y., Aoyagi, T., & Takeuchi, T. (1992). Biosynthesis of Benastatin A. The Journal of Antibiotics, 45(11), 1767–1772. https://doi.org/10.7164/antibiotics.45.1767

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